Our laboratory has elucidated the contribution of rare de novo and inherited mutations to the genetic risk of schizophrenia and develops relevant model systems to understand their impact on neural mechanisms and advance neuropsychiatric therapeutics.
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October 24, 2019
Schizophrenia risk gene linked to cognitive deficits in mice
Restoring “master regulator” reverses behavioral, neuronal abnormalities.
October 09, 2019
Columbia Scientists Reverse Core Symptom of Schizophrenia in Adult Mice
Findings reveal potential new strategy for treating people diagnosed with schizophrenia.
July 27, 2018
New Uses for Old Medications
Even drugs whose development was stalled or canceled might show promise for illnesses they were never meant to treat.