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Our laboratory has elucidated the contribution of rare de novo and inherited mutations to the genetic risk of schizophrenia and develops relevant model systems to understand their impact on neural mechanisms and advance neuropsychiatric therapeutics. 

 

Recent Publication

Alteration of Neuronal Excitability and Short-Term Synaptic Plasticity in the Prefrontal Cortex of a Mouse Model of Mental Illness

Crabtree GW
Sun Z
Kvajo M
Broek JA
Fénelon K
McKellar H
Xiao L
Xu B
Bahn S
O'Donnell JM
Gogos JA